Found 12 matching trials
Effect of SRT2104 on Endotoxin-induced Inflammation PHASE1 SRT2104 is a potent small molecule activator of SIRT1 that has been found t...
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GSK Investigational Site
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A Clinical Trial to Assess the Safety of Oral SRT2104 and Its Effects on Vascular Dysfunction in Otherwise Healthy Cigarette Smokers and Subjects With Type 2 Diabetes Mellitus PHASE1 The primary purpose of this study is to evaluate the safety and tolerabilit...
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GSK Investigational Site
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A Clinical Study to Assess the Effect of Food and Gender on the Pharmacokinetics of SRT2104 Administered as an Oral Suspension or Capsule Formulation to Normal Healthy Volunteers PHASE1 The primary objective of this study is to assess the pharmacokinetic profil...
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GSK Investigational Site
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A Phase 1b Study to Assess the Safety and Anti-inflammatory Effects of Two Different Doses of SRT2104 in Patients With Ulcerative Colitis PHASE1 The purpose of this research study is to:
* 1\) Test the safety and tolera...
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GSK Investigational Site
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A Clinical Study to Assess the Safety, Tolerability and Pharmacokinetics of Oral SRT2104 Capsules Administered to Healthy Elderly Subjects for 28 Days PHASE1 The primary objective is to determine the pharmacokinetics, safety and tole...
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GSK Investigational Site
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A Study to Assess the Relative Bioavailability of New Oral Formulations of SRT2104 in Healthy Male Volunteers PHASE1 This is an open-label, randomized, controlled, single center study to asses...
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GSK Investigational Site
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A Clinical Study to Assess the Safety, Tolerability, and Activity of Oral SRT2104 Capsules Administered for 28 Days to Subjects With Type 2 Diabetes Mellitus PHASE2 Randomized, placebo-controlled, parallel-group, double-blind, multiple-dose...
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GSK Investigational Site
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Study of the Clinical Activity, Safety, and Tolerability of SRT2104 in Subjects With Moderate to Severe Plaque-Type Psoriasis PHASE2 This double-blind, placebo-controlled study will be conducted at 5 study ce...
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A Clinical Study to Assess the Effects of SRT2104 Upon Immobilization-Induced Skeletal Muscle Atrophy in Healthy Human Volunteers PHASE1 The main purpose of this study is to investigate the effect of SRT2104 upon...
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Multiple Locations
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Clinical Study to Assess the Pharmacokinetics, Safety and Tolerability of SRT2104 Administered to Normal Healthy Male Volunteers PHASE1 The purpose of this study is to assess the pharmacokinetic profile, safety,...
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GSK Investigational Site
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